The Wall Street Journal has reported on a paper from the SU2C-PCF Prostate Cancer Dream Team that was published in the prestigious journal Cell. The Cell paper reported that up to 90 percent of samples from patients with advanced prostate cancer harbored some kind of genetic anomaly that was clinically actionable, meaning we have potential treatments to target that specific aberration. The WSJ article focuses specifically on the presence of BRCA1 and BRCA2 genes, which may be treatable with drugs called PARP inhibitors. Dr. Arul Chinnaiyan of the University of Michigan and Dr. Charles Sawyers of Memorial Sloan Kettering Cancer Center, co-leaders of the Dream Team, discuss the significance of the team’s findings in the Journal article, with comment from SU2C SAC Vice-Chair Dr. William Nelson, director of the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.
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