The SU2C Colorectal Cancer Health Equity Dream Team will identify communities near anchor institutions that serve minority and medically underserved communities, pinpoint the unique local needs of those areas, and turn participating at-risk communities into “Stand Up To Cancer Zones” with high rates of colorectal cancer screening. The Dream Team will provide free colorectal cancer testing in the identified zones and will study screening completed via approved tests for colorectal cancer, including primarily colonoscopy and at-home stool tests that analyze fecal DNA and/or blood. The Team also will deploy community health action teams to accompany patients from screening to treatment, and study the effectiveness of this approach. The research will aim to develop better approaches to colorectal cancer interception.